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What Is
Mesothelioma?
Mesothelioma (cancer of the mesothelium) is a disease in which
cells of the mesothelium become abnormal and divide without control or order.
They can invade and damage nearby tissues and organs. Cancer cells can also
metastasize (spread) from their original site to other parts of the body. Most
cases of mesothelioma begin in the pleura or peritoneum.
Mesothelioma is a benign (noncancerous) or malignant (cancerous)
tumor affecting the lining of the chest or abdomen. Exposure to asbestos
particles in the air increases the risk of developing malignant mesothelioma.
The Mesothelioma is a rare form of cancer that involves the mesothelium, or
cells that line an organ, abdominal organs, usually the lungs, and heart. The
most common form of mesothelioma is pleural mesothelioma, where the malignant
tumors form on the pleura, the sac that lines the chest cavity and protects the
lungs. Other forms of mesothelioma affect the peritoneum (abdominal cavity
lining) and the pericardium (which is lining around the heart).
| Mesothelioma In the United
States |
Mesothelioma is usually caused by asbestos exposure. Asbestos
mesothelioma is a fibrous mineral known to be carcinogenic. People who are
exposed to asbestos fibers for just a short period of time (few weeks) or even
to a small amount may be at risk. In particular, people working with asbestos
and their family members or those who live with them develop mesothelioma. There
is a long latency period between initial exposure to asbestos and the
development of malignant tumors. On average, 35-40 years elapse before the onset
of disease.
The early symptoms of mesothelioma can resemble pneumonia,
including shortness of breath, difficulty breathing, persistent cough, chest and
abdominal pain. Often, there is fluid buildup between the pleura and chest
cavity (called pleural effusions), which leads to dyspnea (shortness of breath)
and sometimes pain. Some people may not have any symptoms.
Treatment for
mesothelioma cancer can be surgery to remove the tumors, chemotherapy,
radiation, or a combination of the three. Depending on the person’s health, time
of diagnosis, and other factors, the survival rate is about four to 12 months
from the onset of symptoms. However, occasionally people may live
longer.